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AMPK activator SC4
CAS No. 1364692-88-5
AMPK activator SC4( SC-4 | SC 4 | SC4 )
Catalog No. M11503 CAS No. 1364692-88-5
AMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1413 | In Stock |
|
| 50MG | 2862 | In Stock |
|
| 100MG | 3870 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAMPK activator SC4
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NoteResearch use only, not for human use.
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Brief DescriptionAMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3.
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DescriptionAMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3, the predominant AMPK isoform complexes in human skeletal muscle; does not significantly stimulate activities of the α1-equivalent complexes α1β2γ1 and α1β2γ3 at 5 uM; Deletion β-subunit carbohydrate binding module (CBM) abolished SC4 activation; preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.
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In Vitro——
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In Vivo——
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SynonymsSC-4 | SC 4 | SC4
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PathwayMembrane Transporter/Ion Channel
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TargetAMPK
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RecptorAMPK
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Research Area——
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Indication——
Chemical Information
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CAS Number1364692-88-5
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Formula Weight471.897
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Molecular FormulaC26H18ClN3O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(O)C1=CC(OC2=NC3=CC(Cl)=C(C4=CC=C(C5=CC=CC=C5O)C=C4)N=C3N2)=CC=C1C
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Chemical Name5-((6-Chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4-yl)-3Himidazo[4,5-b]pyridin-2-yl)oxy)-2-methylbenzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ngoei KRW, et al. Cell Chem Biol. 2018 Jun 21;25(6):728-737.e9.
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